Peptide Active Data Details
Basic Peptide Information
DICL ID
DICL_Pep_00324
Ion Channel
Glutamate receptor ionotropic subunit NMDA 2B
Peptide Function
Inhibitor
Gene Name
GRIN2B
Activity Data (nM)
IC50
8220 nM
Ki
Not available
EC50
Not available
Kd
Not available
Biologically Active
Not specified
Sequence Information
Peptide Sequence
NYYLYOAROENSWWT
Peptide UniProt Accession
Not available
UniParc
Not available
Peptide Synonyms/Alias
conotoxin‐Ac1
Peptide Species
Conus achatinus
Peptide Name
Not available
CAS Number
Not available
Experimental Conditions
pH
pH 7.4
Holding Potential (mV)
−70 mV
Temperature
Room Temperture
Test Method
Patch-clamping
Test Species
HEK293 cell (Homo sapiens embryonic kidney 293 cell)
Binding Information
Binding Site
Extracellular domain
Binding Site Residue
N1, Y2, Y3, E10, N11, S12, and T15
Ion Channel Information
Gene Abbreviation (ABB)
i-GluRs
Ion Channel UniProt Accession
Source Organism
Homo sapiens (Human)
References & Disease Information
Disease
Not specified
PubChem CID
Not available
URL
Not available
PMID
Patent
Not available